iPS Cell Line Derived from Alzheimer-Presenillin-1 Mutation


CET.IPS ALZ-500 was created by reprogramming cultured skin fibroblast from a 31-year old Canadian female with first degree relatives with Alzheimer’s disease. The onset of Alzheimer’s disease was diagnosed at age 45. The donor, now deceased, was affected with Alzheimer's disease. The subject has a Presenillin-1 mutation. The target cell was derived from the Coriell repository (Cat# AG07768).